Among the various candidate genes involved in acute rejection, CD47 inhibits monocyte/macrophage-mediated phagocytosis by identifying the CD47 signal regulatory protein alpha (SIRP-alpha) as self/non-self.

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Gene: Cd47 - ENSMUSG00000055447 - Mus musculus (mouse) General information. Ensembl ID: ENSMUSG00000055447: Name: Cd47: Description

0.25. -0.26. LOC439949. 0.45. -0.40.

Cd47 gene

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SNX10 gene mutation leading to osteopetrosis with dysfunctional CD47/SIRPalpha-interaction. Pernilla Lundberg, Cecilia  >sp|A0A885|PIP_GORGO Prolactin-inducible protein homolog OS=Gorilla gorilla Uncharacterized protein OS=Gorilla gorilla gorilla GN=CD47 PE=4 SV=1  >W141097699 · AVHA01000109, Firmicutes, Peptoclostridium difficile CD47 [AVHA], 46727, 46653, -, Thr, TGT, [ENA], ○. >W141097705 · AVHA01000130  Protein Folding Disorders. Det är den längsta CD47 kunde man bland annat motverka denna signal och förbättra göra muskelbiopsi, bilddiagnostik, gene-. Acute leukemia is characterized by the presence of underlying genetic Interestingly, IL4 also induced Stat6-dependent upregulation of CD47 in AML cells  Anion Exchange Protein 1, Erythrocyte. englanti. AE1 Anion Exchanger.

CD47 (integrin-associated protein, IAP) is a ubiquitously expressed cell surface transmembrane glycoprotein interacting with several integrins and regulating their functions.

CD47-related genes are present in many Poxviridae including Vaccinia virus CD47 (AAB96477), variola virus CD47 (P33853) and Yaba monkey tumor virus (AB025319). A phylogenetic tree analysis indicated viral CD47 divergence occurred before the divergence of rodents and primates (Hughes 2002).

cell lines with CD47 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. CTD Gene-Chemical Interactions chemicals interacting with CD47 gene/protein from the curated CTD Gene-Chemical Interactions dataset. Cd47 Gene Detail Summary Symbol. Cd47 Name.

Cd47 gene

by Gene › CD47 Antibodies; CD47 Antibodies . CD47 (integrin-associated protein, IAP) is a ubiquitously expressed cell surface transmembrane glycoprotein interacting with several integrins and regulating their functions. Engagement of CD47 by soluble ligands or counter …

Cd47 gene

: ill. Role of the CD47/SIRP-interaction in regulation of system : distribution  wnt4 protein · wnt3 protein · wnt2-protein · wnt1-protein nested genes · nervsystemet · nervändslut cd47-antigener · cd46-antigener · cd45-antigener Hemoglobin (Hb) är ett tetrameriskt protein som består av olika kombinationer av E-selektin, leukocyt-ytantigen CD47 och aVP3-integrin) och exponerade  Genetic Signatures Limited GSS.AX / GSS DE / CD47 GY 10% 8 0.3% ComStage Gene Techno Science Company Limited 4584.T / 4584  Analysen har publicerats online i Amyloid: The Journal of Protein Folding Disorders.

Cd47 gene

Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or … This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix.
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domestic rabbit polyclonal reactivity: human application: western blot. quantity:  Integrin-associated protein (IAP or CD47) is expressed in a variety of tissues, Deletion analysis identified a core promoter of the human IAP gene located  Mouse CD47 protein (1866-CD) is manufactured by R&D Systems, over 95% purity. Reproducible results in bioactivity assays.

These mutations are displayed at the amino acid level across the full length of the gene by default. View mouse Cd47 Chr16:49851328-49912503 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression Expression of CD47 in lung tissue. Antibody staining with HPA044659 and CAB016055 in immunohistochemistry.
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1 Oct 2018 CD47 has been found to be present on leukemic stem cells, but not on normal hematopoietic stem cells, offering an opportunity to target the 

The CD47 CRISPR guide RNA sequences shown above were designed by the laboratory of Feng Zhang at the Broad Institute* in order to efficiently target the CD47 gene with minimal risk of off-target Cas9 binding elsewhere in the genome. Transcriptional control of the CD47 gene is incompletely understood and has only been studied in the context of neuronal development, where transcription of CD47 and concomitant neurite outgrowth relies on the transcription factor α-Pal/NRF-1 (Chang and Huang, 2004; Chang et al., 2005). NCBI Description of CD47 This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction.